Anti-Salmonella Activity of Volatile Compounds of Vietnam Coriander
Abstract
Essential oil derived from the fresh leaves of Polygonum odoratum Lour was tested for their effects on a foodborne bacterium Salmonella choleraesuis subsp. choleraesuis ATCC 35640 using a broth dilution method.
This essential oil showed a significant antibacterial activity against S. choleraesuis at the concentration of 200 µg/mL. Twenty-five volatile compounds were characterized from this essential oil by GC-MS, and aldehyde compounds were found abundant and accounted for more than three-fourths of the essential oil. Among the compounds characterized, dodecanal (C12) was the most abundant (55.5%), followed by decanal (C10) (11.6%). Both alkanals were effective against S. choleraesuis with the minimum growth inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values of 100 µg/mL. The most potent antibacterial activity against this bacterium was found with two minor compounds, dodecanol (lauryl alcohol) and 2E-dodecenal, both with each MBC of 6.25 µg/mL. Their primary antibacterial action against S. choleraesuis provably comes from their ability to function as nonionic surface-active agents (surfactants), disrupting the native function of integral membrane proteins nonspecifically. Thus, the antibacterial activity is mediated by biophysical processes. In the case of 2E-alkenals, a biochemical mechanism is also somewhat involved, depending on their alkyl chain length.
Abstract
Essential oil derived from the fresh leaves of Polygonum odoratum Lour was tested for their effects on a foodborne bacterium Salmonella choleraesuis subsp. choleraesuis ATCC 35640 using a broth dilution method.
This essential oil showed a significant antibacterial activity against S. choleraesuis at the concentration of 200 µg/mL. Twenty-five volatile compounds were characterized from this essential oil by GC-MS, and aldehyde compounds were found abundant and accounted for more than three-fourths of the essential oil. Among the compounds characterized, dodecanal (C12) was the most abundant (55.5%), followed by decanal (C10) (11.6%). Both alkanals were effective against S. choleraesuis with the minimum growth inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values of 100 µg/mL. The most potent antibacterial activity against this bacterium was found with two minor compounds, dodecanol (lauryl alcohol) and 2E-dodecenal, both with each MBC of 6.25 µg/mL. Their primary antibacterial action against S. choleraesuis provably comes from their ability to function as nonionic surface-active agents (surfactants), disrupting the native function of integral membrane proteins nonspecifically. Thus, the antibacterial activity is mediated by biophysical processes. In the case of 2E-alkenals, a biochemical mechanism is also somewhat involved, depending on their alkyl chain length.
![](https://img2.blogblog.com/img/icon18_edit_allbkg.gif)
![Hướng dẫn download ti liệu M_tả](https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEgeLyykeNmRTIgEEMSBFhCllw0nmDXTfRjohEYdVTcrqE2tLnHbAdGqf9sD9Hx9TXnPu3l37scNDbc5gkz8jmnze-tLVl6Y1-Dtitp9HSl5xU7sHJcrSN4Rbj4jp7xt0sDydiByfzQ7C3jr4Uu-ad6vr15Rir2ksViLK8yR8MkJGv2YT4NK_MssfJzw/s16000/thanks%20donate%202%20(1)%20(1).png)
![](https://4.bp.blogspot.com/-l2sDMPfgOMI/Wv2YrmBrv3I/AAAAAAAAYr4/OlND6ZwM4qIER5xGTsouzziHDHXK9kjjACLcBGAs/s1600/propellar%2Bads1.gif)
![Hướng dẫn download ti liệu M_tả](https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhnMOPv0ws3lQfRxKdAVAwAB10gPWbq0Gll2yx02P6wmFDYHZ-rF_vLfbDM8eaMpBoKJzmaNzc4aDijEDkQtg25RWcuWWbEA0DsCy1QuoTK-mfvr72_mTp7KfUGsVj5JdG5WfYyLel66aHD5mYt8M8O8mx1mog6_biNrgV6slyaz2Lqc9pg7DlHu8JZyR0/s16000/VIPMEMBER27.12.23%20(1).png)
Không có nhận xét nào: