Potential inhibition of biofilm forming bacteria and fungi and DPPH free radicals using Tamarindus indica fruit extract assisted iron oxide nanoparticle (Full)
2 thg 5, 2025 | 11:12

Potential inhibition of biofilm forming bacteria and fungi and DPPH free radicals using Tamarindus indica fruit extract assisted iron oxide nanoparticle (Full)



In this investigation, T. indica fruit extract was used to phyto-synthesize T. indica-Fe2O3 NPs and then they were characterized by bio-physical techniques. The formation of T. indica-Fe2O3 NPs was checked by the development of black colour precipitate. A sharp peak was noticed at 400 nm for T. indica-Fe2O3 NPs by UV–Vis spectroscopy. 

The different XRD peaks denotes the hexagonal shape of T. indica-Fe2O3 NPs and the size of crystallite was 19.8 nm. The role of phytochemicals in the plant extract during NPs synthesis was confirmed by FTIR spectra. The existence of polyhedral shaped NPs measuring 28 nm was noticed through SEM analysis. EDX spectra recorded the weight (%) of elemental iron was 77.91%. The agar well diffusion assay revealed that the prepared T. indica-Fe2O3 NPs showed greater inhibition of E. faecalis and S. aureus (Gram-positive) than K. pneumoniae and E. coli (Gram-negative) at 25 to 100 µg mL−1. Biofilm inhibition of test bacteria and fungi was noted. DPPH scavenging was increased to 71.1% at 100 μg mL−1. This investigation arrives the fact that T. indica-Fe2O3 NPs has the potential to treat bacterial infections and could be employed as a substitute to conventional therapeutic agent in biomedical sector in the future.










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In this investigation, T. indica fruit extract was used to phyto-synthesize T. indica-Fe2O3 NPs and then they were characterized by bio-physical techniques. The formation of T. indica-Fe2O3 NPs was checked by the development of black colour precipitate. A sharp peak was noticed at 400 nm for T. indica-Fe2O3 NPs by UV–Vis spectroscopy. 

The different XRD peaks denotes the hexagonal shape of T. indica-Fe2O3 NPs and the size of crystallite was 19.8 nm. The role of phytochemicals in the plant extract during NPs synthesis was confirmed by FTIR spectra. The existence of polyhedral shaped NPs measuring 28 nm was noticed through SEM analysis. EDX spectra recorded the weight (%) of elemental iron was 77.91%. The agar well diffusion assay revealed that the prepared T. indica-Fe2O3 NPs showed greater inhibition of E. faecalis and S. aureus (Gram-positive) than K. pneumoniae and E. coli (Gram-negative) at 25 to 100 µg mL−1. Biofilm inhibition of test bacteria and fungi was noted. DPPH scavenging was increased to 71.1% at 100 μg mL−1. This investigation arrives the fact that T. indica-Fe2O3 NPs has the potential to treat bacterial infections and could be employed as a substitute to conventional therapeutic agent in biomedical sector in the future.










LINK DOWNLOAD (TÀI LIỆU VIP MEMBER)

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